Knowledge of Pharma

ADU-100 AIR DISPLACEMENT UNIT Ø   The ADU-100 is a dust extraction unit. Ø   It is used for collecting loose powder from them polishing chamber of the DP-100. Ø   It is also used for cleaning operations on automatic capsule filling machines. Ø   The unit removes loose powder, caps, bodies, and capsules lying around the machine. Ø   It can also be coupled with tableting machines for dust collection. METAL DETECTION SYSTEM:      The Metal Detection system works on the Eddy Current Principle using a Focused electromagnetic field.     It uses Dual Channel Phase Sensitive Detection for optimum detection of all metals (ferrous and non-ferrous / non-magnetic stainless steel).        It detects very minute particles of stainless steel and metal flakes inadvertently present in formulations. DP- 100 DE – DUSTING AND POLISHING MACHINE: Ø   The DP-100 is ...

      Ø   The AF-90T is a fully automatic capsule-filling machine that can fill a large variety of powder formulations into hard gelatin capsules. Ø   The machine is formulation friendly and uses a tamping principle to form a slug, which is inserted, into his empty capsule. Ø   A pellet filling / tablet filling / capsule in capsule device are available as an optional attachment. Output • Up to 90,000 capsules / hour for powder filling                Up to 80,000 capsules /hour for pellet filling                Up to 75,000 capsules /hour for tablet filling Ø   Conforming to cGMP. Ø   High filling accuracy due to precise slug dosing principle• Partial filling capability for any size of capsule with extra dosing disc. Ø   Better yield due to high filling accuracy and no po...

The FCE-100 is a high output elevator suitable for elevating from a lower level to higher level. This unit is extremely useful in fully automatic lines where the output from the exit chute of a filling/sorting machine, which is at a lower level, is connected to the inlet chute of a polishing machine, which is at a higher level. Salient Features • Can convey all capsule sizes from 00 to 5 • Inbuilt blower unit • GMP conforming design • All contact parts are of stainless steel approved inert materials

AUTOMATIC CAPSULE FILLING TRANSFER LINE READY TO BLISTER PACK 1. EMPTY CAPSULE SORTER ELEVATOR SE-100 2. AUTOMATIC CAPSULE FILLING M/C [AF-90(T)] 3. AIR DISPLACEMENT UNIT – ADU 4. AUTOMATIC PROCDUCT CONVEYING SYSTEM –PCS – 100 5. ON LINE METAL DETECTION SYSTEM 6. ON LINE CHECK WEIGHER CW- 10 7. DEDUSTING & POLISHING MACHINSE DP – 100 8. MINI CAPSULE SORTER MCS – 100 9. EMPTY CAPSULE ELIMINATOR ECS -100

GELATIN PROPERTIES ACID PIGSKIN FISH BLOOM(G) 0 240-255, 220-260 VISCOSITY, 6.67%,600(MPA,S) 4.2-4.8 3.5-4.5 MOISTURE (%MAX) 13.0 13.0 ASH (%MAX) 1. 1.0 PH ,1% SOLUTION 5.2-5.8 5.5-6.0 ISO IONIC POINT,PH 7.0-9.4 7.0-9.4 PARTICLE SIZE % PASSING 4 US # 100 100 SO2 (PPM MAX) 40 40 H2O2 Absent Absent MICROBIAL STANDARDS TOTAL COUNT 500 500 E.COLI IN 10 GM Absent Absent P. AERUGINOSA IN 10 GM Absent Absent GELATIN SOLUTION: Ø   Raw gelatin and water are mixed in the ratio of 1: 2 and     processed at precise temperature in Safrroys melting systems. Ø   After vacuum is applied, the solution is received in jacketed tanks. Ø   Colors and preservatives are added before taki...

PLANT LAYOUT  FOR CAPSULE MANUFACTURING DEPARTMENT: ENVIRONMENT CONDITION FOR CAPSULE FILLING AREA Humidity:          Not more than 35% RH Temperature:    Not more than 25% Area of each room, position of equipments, washing, drying, and sanitary facilities must be in accordance with GMP. MANUFACTURING PROCESS: CHEMCAPS Limited is an India based young and dynamic organization engaged in the manufacture and export of 'empty hard gelatin capsules' under the brand name of 'Chemlock' for discerning customers around the globe. COMPOSITION                                     Gelatin                                     Water                       ...

HARD GELATIN CAPSULE The hard gelatin capsule consists of a base or body and a shorter cap, which fits firmly over the base of the capsule. ADVANTAGES: 1. They may be used to mask the unpleasant tastes, aromas, or appearance of a drug. 2. They allow powders to be dispensed in an uncompressed form, thus allowing for quicker dissolution and                        absorption of the drug following oral dosing (as compared with tablets). 3. They offer the pharmacist versatility to prepare any dose desired for a variety of administration routes             (e.g. oral, inhalation, rectal, or to be diluted for vaginal, rectal, oral or topical use). 4. They may be easier than tablets for some people to swallow. 5. They can be making to alter the release rate of the drug. 6. They are available ...