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Effect of Micromeritics Property on Preformulation: Particle Size, Particle Shape & Density

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1.       Particle Size: ·          Characterized using these term: o    Very coarse (#8) o    Coarse (#20) o    Moderately coarse (#40) o    Fine (#60) o    Very fine (#80) ·          Size of the particles may be expressed as follows: o    Surface diameter, ds o    Volume diameter, dv o    Projected diameter, dp o    Stokes diameter, dst o    Sieve diameter, dsieve o    Volume – surface diameter, dvs – same volume to surface area ratio Table 1.1: Common Techniques for Measuring Fine Particles of Various Sizes Technique Particle size (micro meters) Microscopic 1-100 Sieve >50 Sedimentation >1 Elutriation   1-50 Cen...

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