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Effect of Organoleptic Properties on preformulation

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1.       Organoleptic Properties: ·          Properties which are evaluated after an impression on the organs of sense . ·          Like, colour, odour, flavour, taste, size, shape, touch, texture etc. ·          A typical preformulation program should beginwith the description of the drug substance. Table 1: Terminology to describe organolepticproperties of pharmaceutical powders. Colour Odour Taste Off-white Pungent Acidic Creamyellow Sulfurous Bitter Tan Fruity Bland Shiny Aromatic Intense Odouerless Sweet Tasteless ·          Color: o    Color is generally a fu...

General Excipients used in Monophasic liquid preparation

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Excipients used in Monophasic Pharmaceutical liquid preparation as below 1.       Vehicle: ·          Purified water ·          Aromatic water: chloroform, peppermint, cinnamon, dill water ·          Syrups ·          Glycerin (glycerites) ·          Elixirs (hydro alcoholic) 2.       Solvents used in internal solution: Solvent Properties Remarks/Use Aqueous liquids Water Cheap, Good solvent action, High dielectric constant, Miscible, Non-Inflammable, Inert Sugar, gum, organic acid, tannins, glycosides, alkaloid salt are soluble easily, Cellulose, starch resin, fixed oil, volatile oils are insoluble Purified water (Di...

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