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CLEARANCE

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CLEARANCE :- Ø   Clearance is the most important parameter in clinical drug applications and is useful in evaluating the mechanism by which a drug is eliminated by the whole organism or by a particular organ. Ø   Clearance is a parameter that relates plasma drug concentration with rate of drug elimination according to following equation:       Clearance = Rate of Elimination             -------15                            Plasma drug concentration                                                   Or Cl = (dx/...

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