Effect of Micromeritics Property on Preformulation: Particle Size, Particle Shape & Density
1. Particle Size: · Characterized using these term: o Very coarse (#8) o Coarse (#20) o Moderately coarse (#40) o Fine (#60) o Very fine (#80) · Size of the particles may be expressed as follows: o Surface diameter, ds o Volume diameter, dv o Projected diameter, dp o Stokes diameter, dst o Sieve diameter, dsieve o Volume – surface diameter, dvs – same volume to surface area ratio Table 1.1: Common Techniques for Measuring Fine Particles of Various Sizes Technique Particle size (micro meters) Microscopic 1-100 Sieve >50 Sedimentation >1 Elutriation 1-50 Cen...