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Dissolution Apparatus 3 & 4 (Reciprocating cylinder & Flow through cells)

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Apparatus: - 3 (Reciprocating Cylinder) Apparatus :- Consists of a set of set of cylindrical, flat bottomed glass vessels; a set of glass reciprocating cylinders; SS fittings & screen that are made of suitable material; and a motor & drive assembly to reciprocate the cylinders. No part of the assembly, including the environment in which the assembly is placed, contributes significant motion, agitation or vibration beyond that due to the smooth, vertically reciprocating cylinders. Reciprocation should be at the tolerance of ± 5% at a distance of 9.9 to 10.1 cm. Apparatus suitability test: - Reference standards:- USP Chlorpheniramine extended  release tablets RS  (For single unit drug release) USP Theophylline extended release beads RS (For multiple units). Dissolution Medium :- Proceed as directed earlier. Procedure: - Place the stated volume of dissolution medium in each vessel of the apparatus. Assemble ...

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