Important term in Pharmacology

Pharmacodynamics                : -  What drug does to the body.

Pharmacokinetics                  : -  What body does to the drug.

Pharmacotherapeutics          : -  Use of drugs in the prevention & treatment of disease.

Clinical pharmacology           : -  Scientific study of drugs in man.

Toxicology                              : -  Aspect of pharmacology deals with adverse effects of

                                                      Drugs.

Pharmacodynamic agents: -  Designed to have pharmacodynamic effects in the                                                                                                                                                                                                      recipient.

Chemotherapeutic agents     : -  Designed to inhibit/kill parasites/malignant cells & does not have or with minimal pharmacodynamic effects in the recipient.

Orphan drugs                         : -  Drugs or Biological Products for diagnosis/treatment/

Prevention of a rare disease.

  E.g.:- Liothyronine (T3), Desmopressin, Baclofen, Digoxin Antibody.

Routes of drug Administration

1)     Oral  2) Parenteral

Injections:-

A)   Intradermal: - given in to layers of skin. E.g.:- BCG vaccine, for testing drug sensitivity.

B)    S.C:- Only non-irritant drugs are given absorption can be enhanced by enzyme Hyalurinase S.C.drug implants can act as depot therapy. E.g.:- steroid hormones.

In children saline is injected in large quantities – Hypodermalysis.

C)    I.M:- Mild irritants, suspensions & colloids can be injected by this route.

D)   I.V:- Directly to the vein.

E)    Intraarterial: - Only used for diagnostic studies. E.g.:- Angiograms, embolism therapy.

F)    Intrathecal: - Spinal anesthetics in to subarachnoid space.

G)   Intra medullary: - Drug introduced to Bone marrow.

Intraarticular & Intra tensional: - Drug administered into joints. E.g.:- Hydrocortisone acetate in rheumatoid arthritis.