General Material used for Nano Formulations
1 Materials
Polymer
|
Stabilizers
Generally surfactants are used as stabilizers to
reduce high surface free energy of nanosized particles.
Generally used stabilizers are-
- Cellulosic
- Poloxamers 184, 188, 338, 407
- Poloxamine 908
- Polysorbates 20, 40, 60, 80
- Lecithins
- Cremophor EZ and RS 40
- Polyoxyethylene lauryl ether
- Povidones
- Lecithin is stabilizer of choice for parenteral preparations.
Organic solvents
Water immiscible
organic solvent :
- Methylene chloride
- Chloroform
- DCM
Partially water
miscible solvent :
- Ethyl acetate
- Ethyl formate
- Butyl lactate
- Triacetin
- Propylene carbonate
- Benzyl alcohol
- Ethanol
- Isopropanol
Co-surfactants
- Bile salts
- Dipotassium Glycerrhizinate
- Transcutol
- Glycofurol
- Ethanol
- IPA
Other additives
- Includes Buffers
- Salts
- Polyols
- Osmogents
- Cryoprotectants
Comments
Post a Comment