Knowledge of Pharma

M/s (Name and address of the company) __________________________________ Name of the product __________________________________________________ (Trade name, if any) (MFR No.) __________________________________________________________ (Batch No.) ____________________________________ Capsule size __________ (Batch size.) ____________________________________ Colour _______________ Date of Expiry _______________________________________________________ Date of commencement ________________________________________________        Sr.No. Ingredients Standards Q/C Report No. Label Claim Quantity Required Quantity actually used Remarks 1 2 3 4 5 6 7 8 TOTAL Raw material initially weighed and measured by _____________________...

Globex Method: The lipophillic fill and the shell formulation are stored in separate containers, both kept warm. The fill and the shell material are pumped through a concentric double capillary, with fill in the inner one. The fill is pumped in pulses to give fill volumes between 20 to 600 mg. Here, the formation of capsule depends upon the interfacial tension between the fill and shell material. The shell material possesses a higher surface tension. In attempt to reduce the surface tension, the droplet is formed. As a result of this the seamless round soft capsules are formed. The end of the double capillary is immersed in a cooling bath containing a liquid usually liquid paraffin which is kept at about 4 ˚C  Advantages: Seamless capsules, which are tamper-evident. Free of contamination or air entrapment. Risk of leakage is minimal. Capacity: 10,000-40,000 capsules per hour. Rotary Die Process: At the same time when two fi...